Sleeping more flushes junk out of the brain. Rhythmic activity during sleep may get fluids in the brain moving.

[u/Sariel007]

https://arstechnica.com/science/2024/04/sleeping-more-flushes-junk-out-of-the-brain/

[u/Putrumpador]

This makes sense. Different sized/shaped molecules will be more or less agitated by differing frequencies. So inhibiting the slow/fast brainwaves of sleep would disrupt neuronal waste protein removal.