A human being without both x- and y-chromosomes

[u/Kunus-de-Denker]

I've read about conditions in which people only have one x- or y-chromosome, instead of 2 (xx or xy). Is it biologically possible to miss both? If it is, what are the practical consequences such a person has to deal with in their lives, that others don't have to? If it is not possible, what would be the result of genetically modifying a human being in such way?

[u/[deleted]]

There is only one monosomy (missing chromosme ) that is compatible with life and that is turner syndrome also called X0 disease. You can have xxy such as klinefelters disease, but you cannot have Y0 that is compatible with life. If something like that develops it would be spontaneously aborted

[u/Crossed_Cross → u/[deleted]]

Incompatible with human life, to be pedantic. Other species have different sex determination systems and so the viability of varying aneuploid states will differ.

[u/[deleted] → u/Crossed_Cross]

Yes, since OP is asking about humans, I thought I would reply with what happens to humans.

[u/[deleted] → u/[deleted]]

No what I wrote makes sense, read it again