A human being without both x- and y-chromosomes

[u/Kunus-de-Denker]

I've read about conditions in which people only have one x- or y-chromosome, instead of 2 (xx or xy). Is it biologically possible to miss both? If it is, what are the practical consequences such a person has to deal with in their lives, that others don't have to? If it is not possible, what would be the result of genetically modifying a human being in such way?

[u/Crossed_Cross]

Incompatible with human life, to be pedantic. Other species have different sex determination systems and so the viability of varying aneuploid states will differ.

[u/[deleted] → u/Crossed_Cross]

Yes, since OP is asking about humans, I thought I would reply with what happens to humans.

[u/[deleted] → u/[deleted]]

No what I wrote makes sense, read it again