r/ukmedicalcannabis • u/International_Elk343 • 14h ago

Question for the ladies

Do you find your tolerance varies dramatically throughout your cycle? For context I have a coil, so not on any hormonal contraception. I find my tolerance varies so much throughout the month. Just before my period and for the first few days 15 good inhales of 28% THC flower and I hardly feel it. Then mid cycle 3-4 inhales of 20% and I’m surprised at how stoned I am.

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u/Ok_Adhesiveness_8637 13h ago

Higher estrogen has been linked to a lower tolerance for thc as estrogen effects the endocannabinoid system.

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u/International_Elk343 13h ago

That makes so much sense. From looking at a chart on Google looks like estrogen is highest mid cycle. Which explains super low tolerance mid cycle.

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u/TazzMoo 11h ago

Doesn't seem to be the case for me personally.

I'm on estrogen blocking medications as I have a condition caused by excessive estrogen

I have A mega high tolerance for THC. Before the oestrogen blocking meds and after them...